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Handbook of Single-Molecule Biophysics, 1st Edition

Handbook of Single-Molecule Biophysics, 1st Edition
Author
Hinterdorfer, Peter (EDT)/ Van Oijen, Antoine (EDT) 
Publisher
Springer-Verlag 
Publication Date
Nov, 2009 
ISBN
0387764968 or 9780387764962
HARDCOVER 
626 Pages
出版済み 3週間でお届けいたします。
The delivery time takes 3 weeks

¥ 30,467 (tax included)

Description

During the last decade, a number of novel biophysical methods have been developed that allow the manipulation and study of individual biomolecules. The ability to monitor biological processes at the fundamental level of sensitivity, that of a single molecule, has given rise to an improved understanding of the underlying molecular mechanisms. Through the removal of ensemble averaging, distributions and fluctuations of molecular properties can be characterized, transient intermediates identified, and catalytic mechanisms elucidated. By applying forces on biomolecules while monitoring their activity, important information can be obtained on how proteins couple function to structure. The Handbook of Single-Molecule Biophysics provides an introduction to these techniques and presents an extensive discussion of the new biological insights obtained from them. Editorial Advisory Board: Daniel Muller, Cheng Zhu, Claus Seidel, Xiaowei Zhuang, Thomas Schmidt, Nynke Dekker.

Contents

Chapter 1 - Single-molecule fluorescence tracking
Ahmet Yildiz (UCSF)

Chapter 2 - Single molecule studies in the membrane
Gerhard Schuetz (Linz)
Thomas Schmidt (Leiden)

Chapter 3 - Single-molecule imaging in live cells
Jie Xiao (Johns Hopkins)

Chapter 4 - Superresolution imaging
Xiaowei Zhuang (Harvard)

Chapter 5 - Fluorescence Resonance Energy Transfer
Achillefs Kapanides (Oxford)

Chapter 6 - Single-molecule enzymology
Antoine van Oijen (Harvard)

Chapter 7 - Rotary proteins
Richard Berry (Oxford)

Chapter 8 - Fluorescence Correlation Spectroscopy
Petra Schwille (Dresden)

Chapter 9 - Advanced Concepts of Fluorescence Fluctuation Spectroscopy
Jorg Enderlein (Tubingen)

Chapter 10 - Nucleic-acid analysis at the single-molecule level
Amit Meller (Boston University)

Chapter 11 - Nanopores: Geneneration and Single-Molecule Applications
Stefan Howorka (UCL)
Zuzanna Siwy (UC-Irvine)

Chapter 12 - Optical trapping
Michael Woodside (Alberta)
Megan Valentine (UCSB)

Chapter 13 - Magnetic tweezing
Nynke Dekker (Delft)

Chapter 14 - Protein/DNA unfolding
Matthias Rief (Munich)

Chapter 15 - Single molecule recognition
Ziv Reich (Weizman)
Peter Hinterdorfer (Linz)

Chapter 16 - Nano-scale AFM imaging
Simon Scheuring (Institut Curie)
Daniel J. Muller (Dresden)

Chapter 17 - High Speed AFM
T. Ando (Kanazawa)

Chapter 18 - Recognition imaging
Yves Dufrene (Leuven)
Peter Hinterdorfer (Linz)

Chapter 19 - Atomic force microscopy of protein-protein interactions
Vincent Moy (Miami)

Chapter 20 - A New Approach to Analysis of Single Molecule Force Measurements
Evan Evans (Vancouver)

Chapter 21 - Single Molecule Recognition: Extracting Information from Individual Binding Events and Their Correlation
Cheng Zhu (Georgia Tech)

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