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Series : Proteases in Biology and Disease

Aminopeptidases in Biology and Disease

Aminopeptidases in Biology and Disease
Author
Hooper, N. M. (EDT)/ Lendeckel, Uwe (EDT) 
Publisher
Kluwer Academic Publishers 
Publication Date
Mar, 2004 
ISBN
030648465X or 9780306484650
HARDCOVER 
354 Pages
版元にて一時品切れ中ですが、ご予約可能です。納期は未定です。
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Description

Aminopeptidases in Biology and Disease provides a comprehensive review of the emerging role of aminopeptidases in a range of biological processes and disease situations. Processes as diverse as angiogenesis, antigen presentation, neuropeptide and hormone processing, pregnancy and reproduction, protein turnover, memory, inflammation, tumour growth, cancer and metastasis, blood pressure and hypertension all critically involve one or more aminopeptidases. The individual chapters have been written by experts in the field who have provided detailed accounts of the central roles played by various aminopeptidases in biology and disease.
Aminopeptidases in Biology and Disease will be a timely and useful source of information both for those immersed in the field of aminopeptidases and those just taking their first steps into this exciting and ever-expecting field of research. Each chapter starts with a brief abstract summarizing the content and biological reference.
Aminopeptidases in Biology and Disease:
-Provides an up-to-date presentation of the role of aminopeptidases in biological processes,
-Highlights the critical role played by aminopeptidases in various diseases,
-Provides background information on the structure and function of each aminopeptidase,
-Covers the use of aminopeptidase inhibitors in therapeutic applications.

Contents

The Puromycin-Sensitive Aminopeptidase: Role in Neurological, Reproductive, Immunological and Proliferative Disorders; M.W. Thompson, L.B. Hersh. Methionine Aminopeptidase: Emerging Role in Angiogenesis; J.A. Vetro, B. Dummitt, Yie-Hwa Chang. Placental Leucine Aminopeptidase; S. Nomura, T. Ito, S. Mizutani. Insulin-Regulated Aminopeptidase; Siew Yeen Chai, R. Fernando, Siying Ye, G.R. Peck, A.L. Albiston. Leukotriene A4 hydrolase: Molecular Properties and Involvement in Inflammation; F. Tholander, A. Wetterholm, J.Z. Haeggstrom. Arginyl Aminopeptidase; S. Cadel, C. Piesse, C. Gouzy-Darmon, P. Cohen, T. Foulon. TRH-Degrading Aminopeptidase: A regulator and terminator of TRH action? K. Bauer. ERAP1 and MHC Class I Antigen Presentation; T. Saric, A.L. Goldberg. CD13/Aminopeptidase N in Tumor Growth and Angiogenesis; N. Petrovic, W. Schacke, L.H. Shapiro. Alanyl-Aminopeptidases in Human T cells: Structures and functions; U. Lendeckel, A. Bukowska, J.H. Lattig, W. Brandt. Aminopeptidase Inhibitors as Anti-Hypertensive Drugs; X. Iturrioz, A. Reaux-Le Goazigo, C. Llorens-Cortes. Aminopeptidase P and Vasoactive Peptides: From fundamental aspects to clinical interests; G. Molinaro, G. Boileau, A. Adam. Nematode aminopeptidases; D.R. Brooks, R.E. Isaac.

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