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Series : Advances in Experimental Medicine and Biology

Photoreceptors and Calcium

Photoreceptors and Calcium
Author
Baehr, Wolfgang, Ph.D. (EDT)/ Palczewski, Krzysztof, Ph.D. (EDT) 
Publisher
Kluwer Academic Publishers 
Publication Date
Feb, 2003 
ISBN
0306474158 or 9780306474156
HARDCOVER 
632 Pages
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¥ 40,986 (tax included)

Description

This volume foxuses on the status of Ca2+ ions in regulation of phototransduction, light adaptation and the recovery phase in vertebrate photoreceptors. Particular emphasis is given to Ca2+-binding proteins and their targets, among them particulate guanylate cyclases, GPCR-coupled kinases and cyclic nucleotide-gated cation channels. The book also expands our understanding of events invovling Ca2+ in the retinal pigment epithelium, in synaptic transmission and secondary retinal neurons. A significant part of the book is dedicated to the role of Ca2+ in invertebrate phototransduction, the best-studied phospholipid-mediated signal transduction pathway. Several chapters explore association of gene defects with human retina disease and the generation of animal models of retinal degeneration.

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