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Series : Advances in Experimental Medicine and Biology

Lymphocyte Activation and Immune Regulation IX

Homeostasis and Lymphocyte Traffic

Lymphocyte Activation and Immune Regulation IX
Author
International Conference on Lymphocyte Activation and Immune Regulation (9th : 2002 : Newport Beach, Calif.)/ Paul, William (EDT) 
Publisher
Kluwer Academic Publishers 
Publication Date
Dec, 2002 
ISBN
030647395X or 9780306473951
HARDCOVER 
218 Pages
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¥ 24,887 (tax included)

Description

This volume is divided into three sections. Section I deals with factors that regulate the development and maturation of T cells and B cells and lymphocyte traffic. The significance of C-kit, Bcl-6, IL-7, and Vav in the development of T and B lymphocytes is discussed. A role of lymphotoxins and VAP-I in trafficking of leucocytes is reviewed. Finally, the trafficking and homing characteristics of T cell and B cell subsets, and the regulation of these processes during the immune response, is presented. Section II discusses various aspects of naive and memory T cell biology, including clonal expansion, reprogramming of genes including those encoding cytokines and cytotoxic granules, changes in the expression of cell surface proteins involved in cell-cell adhesion, homing of naive and memory T cells, the role of MHC and cytokines in the maintenance of naive and memory T cells, and the characterization and differentiation of virus-specific memory T cell heterogeneity in mice and humans. Novel methods of visualization of immune cells and immune systems are reviewed in Section III.

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